Sam50–Mic19–Mic60 axis determines mitochondrial cristae architecture by mediating mitochondrial outer and inner membrane contact
نویسندگان
چکیده
منابع مشابه
The mitochondrial inner membrane protein mitofilin controls cristae morphology.
Mitochondria are complex organelles with a highly dynamic distribution and internal organization. Here, we demonstrate that mitofilin, a previously identified mitochondrial protein of unknown function, controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into ...
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ژورنال
عنوان ژورنال: Cell Death & Differentiation
سال: 2019
ISSN: 1350-9047,1476-5403
DOI: 10.1038/s41418-019-0345-2